ADRIANNE JENNER

My research focuses on the applications of mathematical modelling in medicine. This includes the use of deterministic and stochastic modelling to answer fundamental questions in the treatment of diseases. For the most part my research has been in developing mathematical models, closely calibrated to data, that help to understand cancer formation and treatment. This includes (but is not limited to) oncolytic virotherapy and immunotherapy. More recently, I have been involved in developing systemic and tissue level models of the SARS-CoV-2 systemic and tissue-level immune response to help understand the distinction between severe and mild disease responses.  More recently, I have been working with clinicians to develop a computational model of multiple sclerosis that can be used to help predict patient disease course and help develop new experimental therapies.